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KMID : 1039620160060050457
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Korean Journal of Family Practice
2016 Volume.6 No. 5 p.457 ~ p.463
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The Relationship between Body Mass Index and Homeostasis Model Assessment Index and the Impact of Vitamin D: Based on 2010 Korean National Health and Nutrition Survey
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Park Min-Gyu
Kim Eun-Kyung
Kim Jung-Hun
Lee Je-Won
Kim Jung-Hwan
Cho Chung-Hwan
Lee Jin-Hee
Lee Jae-Sung
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Abstract
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Background: The prevalence of diabetes is increasing worldwide on a daily basis, thus threatening human health. To help control diabetes, considerable research has focused on factors influencing diabetes. Among these factors, obesity is the major cause of diabetes. In addition, vitamin D, which has numerous physiological functions, has been associated with diabetes and obesity. Accordingly, the present study investigated the influence of obesity and vitamin D on diabetes using the Korea National Health and Nutrition Examination Survey (KNHANES) data; we also investigated whether vitamin D is a moderating variable between obesity and insulin resistance, the hallmark characteristic of diabetes.
Methods: KNHANES data from January to December 2010 were used. Physical information was obtained via interviews, physical examinations, and self-administered questionnaire surveys; 25-hydroxyvitamin D levels, along with other factors, were measured using blood tests. Those who did not participate in both the survey and blood test were excluded from the present study.
Results: A greater degree of insulin resistance was associated with a vitamin D deficiency and a higher body mass index (BMI). However, vitamin D did not modify the association between the BMI and insulin resistance.
Conclusion: Although this study aimed to investigate the modulatory action of vitamin D on the association between BMI and insulin resistance, it did not provide evidence of a significant relationship. Insulin resistance was increased in patients with a vitamin D deficiency or a higher BMI. Regular physical activity, especially outdoor activities, as well as vitamin D consumption, are recommended to correct for vitamin D deficiency.
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KEYWORD
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Vitamin D, Insulin Resistance, Bone Mass Index, Korea National Health and Nutrition Examination Survey
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